Clinical Handbook of Pediatric Infectious Disease by Russell W. Steele

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By Russell W. Steele

Within the care of pediatric sufferers, infectious ailments include over 50% of the scientific diagnoses. hence, it's necessary to have a simple realizing of infectious strategies and to maintain abreast of latest advancements within the box. This reference stands as a handy and time-saving reference for clinicians at the prognosis, therapy, and prevention of pediatric infections ailments and is totally up-to-date to incorporate the most recent instructions from esteemed societies similar to the Infectious illness Society of the US, the facilities for illness keep an eye on and Prevention, the yank Thoracic Society, and the yank Academy of Pediatrics.

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Maternal chickenpox in the final 21 days of gestation can result in congenital chickenpox, with infants born to mothers with onset of rash from 5 days before to 2 days after delivery at highest risk for severe infection. Varicella-Zoster immune globulin (VZIG) 125 U IM should be given to these TABLE 14 Treatment for Congenital Syphilis Neonates with physical exam or X ray evidence of active disease, or abnormal CSF findings, or non-treponemal titers 4-fold or greater than mother’s, or maternal treatment absent, unknown, undocumented, non-penicillin, or within 1 mo of delivery, or undocumented fall in maternal nontreponemal titers, or negative workup but uncertain follow-up after discharge Age <4 wks, normal Aqueous crystalline penicillin G 100–150,000 U/kg/day IV or IM div.

Management of the child with a positive blood culture for an organism which is likely a true pathogen depends partly on the infective organism (Table 2). Pneumococcal bacteremia exhibits spontaneous resolution in over 94% of cases and an infrequent rate of subsequent focal infection such as otitis media or pneumonia; therefore, for patients who are afebrile and clinically stable following the initial exam, most experts recommend a follow-up visit, repeat blood cultures, and PO antibiotics. Because meningococcal bacteremia is much more likely to progress to severe infection, particularly meningitis, a more aggressive approach is necessary.

Qd  10 days Age <4 wks, abnormal Aqueous crystalline penicillin G 100,000–150,000 U/kg/day IV div. d. i. CSF d. (>7 days)  10 days Age >4 wks– yr normal Aqueous crystalline penicillin G 200,000 U/kg/day IV div. d.  10 days CSF Age >4 wks–1 yr Aqueous crystalline penicillin G 200,000 U/kg/day IV div. d.  10 days followed by abnormal CSF benzathine penicillin G 50,000 U/kg IM weekly  3 Age >1 yr normal CSF Benzathine penicillin G 50,000 U/kg IM weekly  3 Age >1 yr abnormal Aqueous crystalline penicillin G 200,000–300,000 U/kg/day IV or IM div.

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