Biosensors and Cancer by Victor R. Preedy (ed.), Vinood B. Patel (ed.)

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By Victor R. Preedy (ed.), Vinood B. Patel (ed.)

Realizing the significance and alertness of biosensors is advanced through the varied variety of tools and purposes. additionally, current texts are just a little technical in nature, making it tricky for the beginner. This booklet disseminates details on biosensors in a readable approach, appropriate to a large viewers with various degrees of expertise. issues contain optical imaging, floor plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.

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2003. Near-Infrared Optical Imaging of Proteases in Cancer Mol Cancer Ther 2: 489–496. Mankoff DA. 2007. A Definition of Molecular Imaging. The Journal of Nuclear Medicine 48(6): 18N–21N. Medintz IL, HT Uyeda, ER Goldman and H Mattoussi. 2005. Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mat 4(6): 435–446. Michelini E, M Mirasoli, M Karp et al. 2004. Development of a Bioluminescence Resonance Energy-Transfer Assay for Estrogen-Like Compound in vivo Monitoring. Anal Chem 76: 7069–7076.

32 Biosensors and Cancer the formation of stable SiO2 substrates, the polymer attachment, non-fouling properties, immobilization of probe molecules, and subsequent detection of a target analyte directly from undiluted human serum can all be studied in real-time using a SPR biosensor. The protein, activate leukocyte cell adhesion molecule (ALCAM) was used as a model cancer biomarker. ALCAM is a 105 kDa protein with a normal presence in human blood with evidence for being linked to multiple carcinomas (Ofori-Acquah and King 2008).

Nat Rev Cancer 10: 605–617. Burg TP, M Godin, SM Knudsen, W Shen, G Carlson, JS Foster, K Babcock and SR Manalis. 2007. Weighing of biomolecules, single cells and single nanoparticles in fluid. Nature 446: 1066–1069. Chen SF, J Zheng, LY Li and SY Jiang. 2005. Strong resistance of phosphorylcholine selfassembled monolayers to protein adsorption: Insights into nonfouling properties of zwitterionic materials. J Am Chem Soc 127: 14473–14478. Currie EPK, W Norde and MAC Stuart. 2003. Tethered polymer chains: Surface chemistry and their impact on colloidal and surface properties.

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