Antibiotic Therapy for Geriatric Patients by Thomas T. Yoshikawa, Shobita Rajagopalan

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By Thomas T. Yoshikawa, Shobita Rajagopalan

Written by way of the key specialists at the subject, this reference presents easy access to crucial details on particular antibiotics, significant medical infections, chosen pathogens, and infections in long term elderly-care facilities-summarizing the titanic array of subject matters with regards to infectious illnesses in older adults together with epidemiology, medical manifestations, altered host resistance, and pharmacology

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8 F; 29% were afebrile or hypothermic. 5 F; only 9% were afebrile. Persistent elevation of body temperature of at least 2 F over baseline values in an elderly patient regardless of baseline body temperature should also raise the suspicion of an infectious process. In a retrospective study of 111 nursing home patients, it has been suggested that much of the decreased fever response in this population was because of a low basal temperature (11). In a prospective study by Castle et al. (12) over a 6-month period, at least 1300 temperature measurements were recorded and 44 infectious processes were identified.

Clin Infect Dis 2001; 33:1892–1900. Nicolle LE. Infection control in long-term care facilities. Clin Infect Dis 2000; 31:752–756. Norman DC. Fever in the elderly. Clin Infect Dis 2000; 31(1):148–151. Yoshikawa TT. Epidemiology and unique aspects of aging and infectious diseases. Clin Infect Dis 2000; 30:931–933. 2 Clinical Manifestations of Infections Nancy Hanna and Thomas T. Yoshikawa Department of Internal Medicine, Charles R. –Charles R. A. Key Points:     Typical symptoms and signs of infection may be delayed in onset, atypical, or absent.

Instead of a typical constellation of several specific symptoms of an infectious disease as seen in younger adults, infections in the elderly may have fewer and nonspecific symptoms. Typical nonspecific symptoms and signs that may represent infection in old age are summarized in Table 2. Besides fever, the most common general manifestations of infection in the elderly are falls, delirium, anorexia, or generalized weakness (6,7). It should be mentioned that similar clinical presentations are also commonly seen in geriatric patients with noninfectious diseases, which make infectious diseases all that more difficult to diagnose (7).

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